Active Carbon in America–1914-1957

Adsorption represents the ability of a solid to pull a substance out of a gas or liquid and bind it to its surface. The large surface area of active carbon (l,000 to 2,000 square yards per gram) provides ample space on which substances can be adsorbed. The chemical nature of the substance to be adsorbed is an important factor. Under similar adsorption conditions, phenol is more adsorbable than acetic acid. In the original process used for manufacturing penicillin, active carbon was added to the fermented broth containing about 30 ppm of penicillin. After removal from the broth, the carbon was extracted with acidified menthanol, which eluted and adsorbed penicillin in a relatively concentrated form.

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